Search
Now showing items 1-2 of 2
Nerve growth factor-mediated inhibition of apoptosis post-caspase activation is due to removal of active caspase-3 in a lysosome-dependent manner
(Springer Nature, 2014-05-01)
Nerve growth factor (NGF) is well characterised as an important pro-survival factor in neuronal cells that can inhibit apoptotic cell death upstream of mitochondrial outer membrane permeabilisation. Here we addressed the ...
Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under er stress conditions
(Informa UK Limited, 2014-11-02)
Endoplasmic reticulum (ER) stress-induced cell death is normally associated with activation of the mitochondrial apoptotic pathway, which is characterized by CYCS (cytochrome c, somatic) release, apoptosome formation, and ...