Now showing items 1-6 of 6
Role of micro-rnas in breast cancer surgery
Background: The management of breast cancer has changed dramatically in the molecular era. Micro-RNAs can contribute to multiple facets of cancer surgery. Methods: This narrative review, based on years of research on the ...
Red algal extracts from plocamium lyngbyanum and ceramium secundatum stimulate osteogenic activities in vitro and bone growth in zebrafish larvae
(Springer Nature, 2018-05-16)
Through the current trend for bioprospecting, marine organisms-particularly algae-are becoming increasingly known for their osteogenic potential. Such organisms may provide novel treatment options for osteoporosis and other ...
Implantation of hyaluronic acid hydrogel prevents the pain phenotype in a rat model of intervertebral disc injury
(American Association for the Advancement of Science (AAAS), 2018-04-01)
Painful intervertebral disc degeneration is mediated by inflammation that modulates glycosylation and induces hyperinnervation and sensory sensitization, which result in discogenic pain. Hyaluronic acid (HA) used as a ...
Vitamin d receptor variants and uncontrolled asthma
(Edra SpA, 2018-01-01)
Background. Asthma is a common childhood respiratory disease, affecting around 20% of Irish children. In other populations, vitamin D receptor (VDR) polymorphisms have been associated with asthma risk. We aimed to investigate ...
Anti-cancer activity of phenyl and pyrid-2-yl 1,3-substituted benzo[1,2,4]triazin-7-ones and stable free radical precursors
(MDPI AG, 2018-03-03)
Cell viability studies for benzo[1,2,4]triazin-7-ones and 1,2,4-benzotriazinyl (Blatter-type) radical precursors are described with comparisons made with 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO). All of the stable free ...
Centrobin controls primary ciliogenesis in vertebrates
(Rockefeller University Press, 2018-02-13)
The BRCA2 interactor, centrobin, is a centrosomal protein that has been implicated in centriole duplication and microtubule stability. We used genome editing to ablate CNT ROB in hTERT-RPE1 cells and observed an increased ...