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Macromolecularly crowded in vitro microenvironments accelerate the production of extracellular matrix-rich supramolecular assemblies
(Springer Nature, 2015-03-04)
Therapeutic strategies based on the principles of tissue engineering by self-assembly put forward the notion that functional regeneration can be achieved by utilising the inherent capacity of cells to create highly ...
A search for spectral hysteresis and energy-dependent time lags from x-ray and tev gamma-ray observations of mrk 421
(American Astronomical Society, 2016-12-22)
Blazars are variable emitters across all wavelengths over a wide range of timescales, from months down to minutes. It is therefore essential to observe blazars simultaneously at different wavelengths, especially in the ...
Benthos distribution modelling and its relevance for marine ecosystem management
(Oxford University Press (OUP), 2014-06-19)
Marine benthic ecosystems are difficult to monitor and assess, which is in contrast to modern ecosystem-based management requiring detailed information at all important ecological and anthropogenic impact levels. Ecosystem ...
Family and healthcare professionals’ perceptions of a pilot hospice at home programme for children: a qualitative study
(Springer Nature, 2016-10-28)
Background: Parents commonly report a significant improvement in quality of life following the provision of hospice and supportive care and have identified a need for such a service in the home. The purpose of this study ...
Protein charge determination and implications for interactions in cell extracts
(Wiley-Blackwell, 2016-12-01)
Decades of dilute-solution studies have revealed the influence of charged residues on protein stability, solubility and stickiness. Similar characterizations are now required in physiological solutions to understand the ...
Grasping the nature of the cell interior: fromphysiological chemistrytochemical biology
(Wiley-Blackwell, 2016-05-11)
Current models of the cell interior emphasise its crowded, chemically complex and dynamically organised structure. Although the chemical composition of cells is known, the cooperative intermolecular interactions that govern ...
Nucleolar activity and cenp-c regulate cenp-a and cal1 availability for centromere assembly in meiosis
(The Company of Biologists, 2016-04-15)
The centromere-specific histone CENP-A is the key epigenetic determinant of centromere identity. Whereas most histones are removed from mature sperm, CENP-A is retained to mark paternal centromeres. In Drosophila males we ...