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Now showing items 71-80 of 80
Perceived risk of mental health problems in primary care
(Frontiers Media SA, 2015-11-17)
In the face of limited resources and an aging population with increasingly care needs, healthcare systems must identify community-dwelling older adults with mental health problems at higher risk of adverse outcomes such ...
A 3′-untranslated region kras variant and triple-negative breast cancer: a case-control and genetic analysis
(Elsevier BV, 2011-04-01)
Background We previously identified a functional variant in a let-7 microRNA (miRNA) complementary site in the 3'-untranslated region of the KRAS oncogene (rs61764370) which is associated with cancer. We aimed to investigate ...
Association of high-sensitivity c-reactive protein with de novo major depression
(Royal College of Psychiatrists, 2010-10-29)
Background
Although there is cross-sectional evidence that changes in the immune system contribute to the pathophysiology of depression, longitudinal data capable of elucidating cause and effect relationships are ...
Genetic variation indnmt3band increased global dna methylation is associated with suicide attempts in psychiatric patients
(Wiley-Blackwell, 2012-10-26)
Recently, a significant epigenetic component in the pathology of suicide has been realized. Here we investigate candidate functional SNPs in epigenetic-regulatory genes, DNMT1 and DNMT3B, for association with suicide attempt ...
Abnormal glucose tolerance post-gestational diabetes mellitus as defined by the international association of diabetes and pregnancy study groups criteria
(BioScientifica, 2016-07-15)
Objective: An increase in gestational diabetes mellitus (GDM) prevalence has been demonstrated across many countries with adoption of the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) ...
Atlantic dip: simplifying the follow-up of women with previous gestational diabetes
(BioScientifica, 2013-10-03)
Objective: Previous gestational diabetes (GDM) is associated with a significant lifetime risk of type 2 diabetes. In this study, we assessed the performance of HbA1c and fasting plasma glucose (FPG) measurements against ...
Chronic disease burden associated with overweight and obesity in ireland: the effects of a small bmi reduction at population level
(Springer Nature, 2014-02-10)
Background: Overweight and obesity prevalence has risen dramatically in recent decades. While it is known that overweight and obesity is associated with a wide range of chronic diseases, the cumulative burden of chronic ...
Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the enigma consortium
(Springer Nature, 2015-06-02)
The profile of brain structural abnormalities in schizophrenia is still not fully understood, despite decades of research using brain scans. To validate a prospective meta-analysis approach to analyzing multicenter ...
Nodal-stage classification in invasive lobular breast carcinoma: influence of different interpretations of the ptnm classification
(American Society of Clinical Oncology (ASCO), 2010-02-20)
Purpose
Application of current nodal status classification is complicated in lobular breast carcinoma metastases. The aim of this study was to define the optimal interpretation of the pTNM classification in sentinel node ...
Is a motivational interviewing based lifestyle intervention for obese pregnant women across europe implemented as planned? process evaluation of the dali study
(Springer Nature, 2017-09-07)
Background: Process evaluation is an essential part of designing and assessing complex interventions. The vitamin D and lifestyle intervention study (DALI) study is testing different strategies to prevent development of ...