Search
Now showing items 71-80 of 86
Antioxidant and cytoprotective activities of fucus spiralis seaweed on a human cell in vitro model
(MDPI AG, 2017-01-29)
Antioxidants play an important role as Reactive Oxygen Species (ROS) chelating agents and, therefore, the screening for potent antioxidants from natural sources as potential protective agents is of great relevance. The ...
Recent trends in clot retrieval devices: a review
(Springer Nature, 2017-07-12)
Stroke is the second leading cause of death worldwide and in Europe. Even with gold standard medical management of acute ischemic stroke, which is intravenous (IV) thrombolysis by administration of recombinant tissue ...
Effectiveness of a smartphone application to promote physical activity in primary care: the smart move randomised controlled trial
(Royal College of General Practitioners, 2014-06-30)
Background
Physical inactivity is a major, potentially modifiable, risk factor for cardiovascular disease, cancer, and other chronic diseases. Effective, simple, and generalisable interventions that will increase physical ...
Mutsβ and histone deacetylase complexes promote expansions of trinucleotide repeats in human cells
(Oxford University Press (OUP), 2012-08-30)
Trinucleotide repeat (TNR) expansions cause at least 17 heritable neurological diseases, including Huntington's disease. Expansions are thought to arise from abnormal processing of TNR DNA by specific trans-acting proteins. ...
The digital revolution in phenotyping
(Oxford University Press (OUP), 2015-09-29)
Phenotypes have gained increased notoriety in the clinical and biological domain owing to their application in numerous areas such as the discovery of disease genes and drug targets, phylogenetics and pharmacogenomics. ...
Using pm2.5 concentrations to estimate the health burden from solid fuel combustion, with application to irish and scottish homes
(Springer Nature, 2013-06-19)
Background: This study estimates the potential population health burden from exposure to combustion-derived particulate air pollution in domestic settings in Ireland and Scotland.
Methods: The study focused on solid fuel ...
Atlantic dip: high prevalence of abnormal glucose tolerance post partum is reduced by breast-feeding in women with prior gestational diabetes mellitus
(BioScientifica, 2011-09-21)
Objective: Gestational diabetes (GDM) is associated with adverse fetal and maternal outcomes, and identifies women at risk of future type 2 diabetes mellitus (T2DM). Breast-feeding may improve post partum maternal glucose ...
Occipitocervical fusion – an epidemiological drift experienced in an irish tertiary spinal referral center: twenty-year follow-up study
(Medknow, 2017-01-01)
Background: Occipitocervical disease is common in the elderly population, and is on the rise due to an increasingly aging population.
Methods: We retrospectively reviewed all patients who underwent occipitocervical fusion ...
Implementing a peer-support intervention for people with type 2 diabetes: a qualitative study
(Oxford University Press (OUP), 2013-07-08)
This qualitative study aimed to explore participants, peer supporters and practice nurses experience of the implementation of a peer-support intervention for people with type 2 diabetes.
The study was conducted in family ...
Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model
(Springer Nature, 2013-01-01)
Introduction: Diabetic foot ulceration is the leading cause of amputation in people with diabetes mellitus. Peripheral vascular disease is present in the majority of patients with diabetic foot ulcers. Despite standard ...