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Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
(Springer Nature, 2017-10-23)
Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease(1). We conducted a GWAS using 21,468 ER-negative ...
Isolation of streptococcus agalactiae and an aquatic birnavirus from doctor fish garra rufa l
(Springer Nature, 2013-01-01)
Background: The doctor fish, Garra rufa, has become increasingly popular as a treatment for skin disorders and for pedicures in recent years. Despite this there is very little information available regarding the welfare ...
Genetic diversity and associated pathology of rhabdovirus infections in farmed and wild perch perca fluviatilis in ireland
(Inter-Research Science Center, 2014-12-02)
Rhabdovirus infections are an emerging problem for both wild and farmed freshwater fish in Northern Europe. In October 2005, a clinical outbreak with an approximate mortality rate of 40% occurred in a single batch of ...
Sternal metastasis - the forgotten column and its effect on thoracic spine stability
(Baishideng Publishing Group Inc., 2017-01-01)
Sternal metastases are not studied extensively in the literature. There is a paucity of information on their role in metastatic disease. The concept of the fourth column was described by Berg in 1993, and has been proven ...
Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis
(Springer Nature, 2015-02-05)
Psoriatic arthritis (PsA) is a chronic inflammatory arthritis associated with psoriasis and, despite the larger estimated heritability for PsA, the majority of genetic susceptibility loci identified to date are shared with ...
Resolution of a protracted serogroup b meningococcal outbreak with whole-genome sequencing shows interspecies genetic transfer
(American Society for Microbiology, 2016-09-14)
A carriage study was undertaken (n = 112) to ascertain the prevalence of Neisseria spp. following the eighth case of invasive meningococcal disease in young children (5 to 46 months) and members of a large extended indigenous ...
Multidimensional severity assessment in bronchiectasis: an analysis of seven european cohorts
(BMJ, 2016-08-11)
Introduction Bronchiectasis is a multidimensional disease associated with substantial morbidity and mortality. Two disease-specific clinical prediction tools have been developed, the Bronchiectasis Severity Index (BSI) and ...
Obstetric nephrology: lupus and lupus nephritis in pregnancy
(American Society of Nephrology (ASN), 2012-08-09)
SLE is a multi-organ autoimmune disease that affects women of childbearing age. Renal involvement in the form of either active lupus nephritis (IN) at the time of conception, or a IN new onset or flare during pregnancy ...
The association of serum levels of brain-derived neurotrophic factor with the occurrence of and recovery from delirium in older medical inpatients
(Hindawi Limited, 2017-01-01)
Limited studies of the association between BDNF levels and delirium have given inconclusive results. This prospective, longitudinal study examined the relationship between BDNF levels and the occurrence of and recovery ...
Demography and biochemistry of 2800 patients from a renal stones clinic
(SAGE Publications, 2013-02-21)
Background: Because the causes of stones are uncertain, interventions to prevent recurrence have an insecure foundation. Progress depends on careful evaluation of stone formers.
Methods: A descriptive retrospective database ...