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Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer
(American Association for Cancer Research (AACR), 2011-07-27)
Prevalence and predictors of bedrail use in an acute hospital
(Oxford University Press (OUP), 2014-07-10)
Objective: to determine the prevalence and predictors of bedrail use in an acute hospital.
Design and setting: overnight survey in a University teaching hospital.
Subjects: Three-hundred and twenty-seven beds and patients ...
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer
(Springer Nature, 2015-03-09)
Genome-wide association studies (GWAS) and large-scale replication studies have identified common variants in 79 loci associated with breast cancer, explaining similar to 14% of the familial risk of the disease. To identify ...
Common non-synonymous snps associated with breast cancer susceptibility: findings from the breast cancer association consortium
(Oxford University Press (OUP), 2014-06-18)
Candidate variant association studies have been largely unsuccessful in identifying common breast cancer susceptibility variants, although most studies have been underpowered to detect associations of a realistic magnitude. ...
A large-scale assessment of two-way snp interactions in breast cancer susceptibility using 46 450 cases and 42 461 controls from the breast cancer association consortium
(Oxford University Press (OUP), 2013-11-15)
Part of the substantial unexplained familial aggregation of breast cancer may be due to interactions between common variants, but few studies have had adequate statistical power to detect interactions of realistic magnitude. ...
Investigating the association of rs2910164 with cancer in irish patients
(BioScientifica, 2017-09-12)
Introduction: MicroRNAs (miRNAs) are small noncoding RNA molecules that exert post-transcriptional effects on gene expression by binding with cis-regulatory regions in target messenger RNA (mRNA). Polymorphisms in genes ...
Sodium intake and renal outcomes: a systematic review
(Oxford University Press (OUP), 2014-02-07)
BACKGROUND
Sodium intake is an important determinant of blood pressure; therefore, reduction of intake may be an attractive population-based target for chronic kidney disease (CKD) prevention. Most guidelines recommend ...
Psychological coping and recurrent major adverse cardiac events following acute coronary syndrome
(Royal College of Psychiatrists, 2015-05-07)
Background
Depressed mood and stress are associated with recurrent adverse outcomes following acute coronary syndrome (ACS), but the impact of psychological coping style has not been evaluated in detail.
Aims
We tested the ...
The risk instrument for screening in the community (risc): a new instrument for predicting risk of adverse outcomes in community dwelling older adults
(Springer Nature, 2015-07-30)
Background: Predicting risk of adverse healthcare outcomes, among community dwelling older adults, is difficult. The Risk Instrument for Screening in the Community (RISC) is a short (2-5 min), global subjective assessment ...
Effects of znf804a on auditory p300 response in schizophrenia
(Springer Nature, 2014-01-14)
The common variant rs1344706 within the zinc-finger protein gene ZNF804A has been strongly implicated in schizophrenia (SZ) susceptibility by a series of recent genetic association studies. Although associated with a pattern ...