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Redox homeostasis and age-related deficits in neuromuscular integrity and function
(Wiley-Blackwell, 2017-07-26)
Skeletal muscle is a major site of metabolic activity and is the most abundant tissue in the human body. Age-related muscle atrophy (sarcopenia) and weakness, characterized by progressive loss of lean muscle mass and ...
Extended poisson–tweedie: properties and regression models for count data
(SAGE Publications, 2017-08-30)
We propose a new class of discrete generalized linear models based on the class of Poisson-Tweedie factorial dispersion models with variance of the form mu + phi mu(p), where mu is the mean and phi and p are the dispersion ...
Amyotrophic lateral sclerosis patient ipsc-derived astrocytes impair autophagy via non-cell autonomous mechanisms
(Springer Nature, 2017-06-13)
Amyotrophic lateral sclerosis, a devastating neurodegenerative disease, is characterized by the progressive loss of motor neurons and the accumulation of misfolded protein aggregates. The latter suggests impaired proteostasis ...
New hilbert dynamic inequalities on time scales
(Element d.o.o., 2017-01-01)
In this paper, we prove some new dynamic inequalities of Hilbert type on time scales. From these inequalities, as special cases, we will formulate some special integral and discrete inequalities. The main results are proved ...
Effect of logarithmic and linear frequency scales on parametric modelling of tissue dielectric data
(IOP Publishing, 2017-02-03)
The dielectric properties of biological tissues have been studied widely over the past half-century. These properties are used in a vast array of applications, from determining the safety of wireless telecommunication ...
Top-down and bottom-up aerosol–cloud closure: towards understanding sources of uncertainty in deriving cloud shortwave radiative flux
(Copernicus GmbH, 2017-08-22)
Top-down and bottom-up aerosol-cloud shortwave radiative flux closures were conducted at the Mace Head Atmospheric Research Station in Galway, Ireland, in August 2015. This study is part of the BACCHUS (Impact of Biogenic ...
Ticks and tick-borne diseases in Ireland
(Springer Nature, 2017-01-31)
Throughout Europe interest in tick-borne agents is increasing, particularly with regard to those that can cause human disease. The reason for this is the apparent rise in the incidence of many tick-borne diseases (TBD's). ...
Production of a recombinant swollenin from trichoderma harzianum in escherichia coli and its potential synergistic role in biomass degradation
(Springer Nature, 2017-05-16)
Background: Fungal swollenins (SWOs) constitute a class of accessory proteins that are homologous to canonical plant expansins. Expansins and expansin-related proteins are well known for acting in the deagglomeration of ...
Shake table assessment of gusset plate connection behaviour in concentrically braced frames
(Elsevier BV, 2017-11-01)
Botulinum toxin injection versus topical nitrates for chronic anal fissure- an updated systematic review and meta-analysis of randomised controlled trials
(Wiley-Blackwell, 2017-11-22)
AimChronic anal fissures (CAFs) are frequently encountered in coloproctology clinics. Chemical sphincterotomy with pharmacological agents is recommended as first-line therapy. Topical nitrates (TN) heal CAF effectively but ...