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Now showing items 201-209 of 209
Mrc1, tof1 and csm3 inhibit cag·ctg repeat instability by at least two mechanisms
(Elsevier BV, 2008-04-01)
Trinucleotide repeats frequently expand and contract in humans and model organisms. Protein factors that modulate this process have been found by candidate gene approaches or mutant screens for increased expansion rates. ...
Dr4-selective tumor necrosis factor-related apoptosis-inducing ligand (trail) variants obtained by structure-based design
(American Society for Biochemistry & Molecular Biology (ASBMB), 2008-05-12)
Tumor necrosis factor-related apoptosis-inducing ligand ( TRAIL) is a potential anticancer agent that selectively induces apoptosis in a variety of cancer cells by interacting with death receptors DR4 and DR5. TRAIL can ...
High speed optical wavefront sensing with low cost fpgas
(Walter de Gruyter GmbH, 2008-01-01)
This paper outlines a study into deployment of a parallel processing scheme on an FPGA to meet the needs of high bandwidth processing in adaptive optics wavefront sensing. By exploiting a multi-stage pipeline approach we ...
Effect of basolateral adenosine triphosphate on chloride secretion by bovine oviductal epithelium1
(Oxford University Press (OUP), 2008-06-01)
The composition of the fluid within the oviduct is largely determined by the secretory and absorptive activities of the oviduct epithelium. The present study explored the effects of basolateral nucleotide stimulation on ...
Newly identified genetic risk variants for celiac disease related to the immune response
(Springer Nature, 2008-03-02)
Our genome-wide association study of celiac disease previously identified risk variants in the IL2-IL21 region. To identify additional risk variants, we genotyped 1,020 of the most strongly associated non-HLA markers in ...
Effects of repeated cycles of acid challenge and growth on the phenotype and virulence ofsalmonella enterica
(Wiley-Blackwell, 2008-11-01)
Aims: The aim of the study was to investigate how stresses like low pH, which may be encountered in farms or food preparation premises, shape populations of Salmonella enterica by the selection of stress-resistant ...
Salivary muc7 is a major carrier of blood group i type o-linked oligosaccharides serving as the scaffold for sialyl lewis x
(Oxford University Press (OUP), 2008-11-29)
Isolation of salivary MUC7 with gel electrophoresis allowed analysis by LC-MS and LC-MS(2) of released O-linked oligosaccharides and a thorough description of the glycosylation of this molecule, where high-molecular-weight ...
Effects of shearing at housing, grass silage feed value and extended grazing herbage allowance on ewe and subsequent lamb performance
(Cambridge University Press (CUP), 2008-09-26)
The study involved 120 crossbred ewes (sixty 1.5 years old animals and sixty 2.5 years old animals; initial liveweight 67.6 kg, condition score 3.7), that were mated in October They were assigned to six treatments (two ...
A study of gas exchange during the transition from deep winter mixing to spring bloom in the bay of biscay measured by continuous observation from a ship of opportunity
(Informa UK Limited, 2008-01-01)
Monitoring from ships of opportunity allows a wide range of parameters to be measured; thereby extending the coverage of operational oceanographic studies. Observation of dissolved oxygen using new sensors offers an effective ...