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Now showing items 11-18 of 18
Genome-wide association studies identify four er negative–specific breast cancer risk loci
(Springer Nature, 2013-03-27)
Estrogen receptor (ER)-negative tumors represent 20-30% of all breast cancers, with a higher proportion occurring in younger women and women of African ancestry. The etiology and clinical behavior of ER-negative tumors are ...
Differential distribution of competence for panplacodal and neural crest induction to non-neural and neural ectoderm
(The Company of Biologists, 2012-02-08)
It is still controversial whether cranial placodes and neural crest cells arise from a common precursor at the neural plate border or whether placodes arise from non-neural ectoderm and neural crest from neural ectoderm. ...
Effect of progesterone on embryo survival
(Cambridge University Press (CUP), 2008-07-07)
Increased genetic selection over the past 40 years has resulted in a dairy cow with an improved biological efficiency for producing milk but with an associated reduced fertility. Embryo loss is the greatest factor contributing ...
Cloning, overexpression in escherichia coli, and characterization of a thermostable fungal acetylxylan esterase from talaromyces emersonii
(American Society for Microbiology, 2012-03-09)
The gene encoding an acetylxylan esterase (AXE1) from the thermophilic ascomycete Talaromyces etnersonii was cloned, expressed in Escherichia coli, and characterized. This form of AXE1, rTeAXE1, exhibits increased ...
Tumor microenvironment-based feed-forward regulation of nos2 in breast cancer progression
(Proceedings of the National Academy of Sciences, 2014-04-14)
Inflammation is widely recognized as an inducer of cancer progression. The inflammation-associated enzyme, inducible nitric oxide synthase (NOS2), has emerged as a candidate oncogene in estrogen receptor (ER)-negative ...
New roles for nanos in neural cell fate determination revealed by studies in a cnidarian
(The Company of Biologists, 2013-05-09)
Nanos is a pan-metazoan germline marker, important for germ cell development and maintenance. In flies, Nanos also acts in posterior and neural development, but these functions have not been demonstrated experimentally in ...
<i>phip</i> - a novel candidate breast cancer susceptibility locus on 6q14.1
(Impact Journals, LLC, 2017-11-28)
Most non-BRCA1/2 breast cancer families have no identified genetic cause. We used linkage and haplotype analyses in familial and sporadic breast cancer cases to identify a susceptibility locus on chromosome 6q. Two independent ...
Towards precision medicine: discovering novel gynecological cancer biomarkers and pathways using linked data
(Springer Nature, 2017-09-19)
Background: Next Generation Sequencing (NGS) is playing a key role in therapeutic decision making for the cancer prognosis and treatment. The NGS technologies are producing a massive amount of sequencing datasets. Often, ...