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The digital revolution in phenotyping
(Oxford University Press (OUP), 2015-09-29)
Phenotypes have gained increased notoriety in the clinical and biological domain owing to their application in numerous areas such as the discovery of disease genes and drug targets, phylogenetics and pharmacogenomics. ...
Using pm2.5 concentrations to estimate the health burden from solid fuel combustion, with application to irish and scottish homes
(Springer Nature, 2013-06-19)
Background: This study estimates the potential population health burden from exposure to combustion-derived particulate air pollution in domestic settings in Ireland and Scotland.
Methods: The study focused on solid fuel ...
Atlantic dip: high prevalence of abnormal glucose tolerance post partum is reduced by breast-feeding in women with prior gestational diabetes mellitus
(BioScientifica, 2011-09-21)
Objective: Gestational diabetes (GDM) is associated with adverse fetal and maternal outcomes, and identifies women at risk of future type 2 diabetes mellitus (T2DM). Breast-feeding may improve post partum maternal glucose ...
Occipitocervical fusion – an epidemiological drift experienced in an irish tertiary spinal referral center: twenty-year follow-up study
(Medknow, 2017-01-01)
Background: Occipitocervical disease is common in the elderly population, and is on the rise due to an increasingly aging population.
Methods: We retrospectively reviewed all patients who underwent occipitocervical fusion ...
Implementing a peer-support intervention for people with type 2 diabetes: a qualitative study
(Oxford University Press (OUP), 2013-07-08)
This qualitative study aimed to explore participants, peer supporters and practice nurses experience of the implementation of a peer-support intervention for people with type 2 diabetes.
The study was conducted in family ...
Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model
(Springer Nature, 2013-01-01)
Introduction: Diabetic foot ulceration is the leading cause of amputation in people with diabetes mellitus. Peripheral vascular disease is present in the majority of patients with diabetic foot ulcers. Despite standard ...
Fractional flow reserveto guide and to assesscoronary artery bypass grafting
(Oxford University Press (OUP), 2016-12-23)
The aim of this review is to highlight the role of invasive functional evaluation in patients in whom coronary artery bypass graft (CABG) is indicated, and to examine the clinical evidence available in favour of fractional ...
Quality of care and practice patterns in anaemia management at specialist kidney clinics in ireland: a national study
(Oxford University Press (OUP), 2017-07-13)
Background: Although anaemia is a common complication of advanced chronic kidney disease (CKD), knowledge of quality of care and management practices in specialist clinics varies. We examined anaemia practices at specialist ...
Urinary sodium and potassium excretion and risk of cardiovascular events
(American Medical Association (AMA), 2011-11-23)
Context The precise relationship between sodium and potassium intake and cardiovascular (CV) risk remains uncertain, especially in patients with CV disease.
Objective To determine the association between estimated urinary ...
Cognitive impairment and risk of cardiovascular events and mortality
(Oxford University Press (OUP), 2012-05-02)
Cognitive impairment may increase the risk of all cardiovascular (CV) events. We prospectively evaluated the independent association between Mini-Mental State Examination (MMSE) score and myocardial infarction, stroke, ...