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Identification of novel cis-regulatory elements of eya1 in xenopus laevis using bac recombineering
(Springer Nature, 2017-11-03)
The multifunctional Eya1 protein plays important roles during the development of cranial sensory organs and ganglia, kidneys, hypaxial muscles and several other organs in vertebrates. Eya1 is encoded by a complex locus ...
A gene regulatory network underlying the formation of pre-placodal ectoderm in xenopus laevis
(Springer Nature, 2018-07-16)
Background: The neural plate border ectoderm gives rise to key developmental structures during embryogenesis, including the neural crest and the preplacodal ectoderm. Many sensory organs and ganglia of vertebrates develop ...
Overexpression of wnt5a in mouse epidermis causes no psoriasis phenotype but an impairment of hair follicle anagen development
(Wiley-Blackwell, 2014-10-10)
Increased Wnt5a expression has been observed in psoriatic plaques. However, whether Wnt5a overexpression directly causes psoriasis is unknown. In this study, we generated transgenic (TG) mice with epidermal Wnt5a overexpression ...
Early growth response-1 is a regulator of dr5-induced apoptosis in colon cancer cells
(Springer Nature, 2010-01-19)
Thiamine plays a critical role in the acid tolerance of listeria monocytogenes
(Oxford University Press (OUP), 2011-11-14)
Understanding the molecular basis of acid tolerance in the food-borne pathogen Listeria monocytogenes is important as this property contributes to survival in the food-chain and enhances survival within infected hosts. The ...
Single nucleotide polymorphisms within the bovine dlk1-dio3 imprinted domain are associated with economically important production traits in cattle
(Oxford University Press (OUP), 2010-09-03)
Previous studies show that DNA sequence variation within the mammalian DLK1-DIO3 imprinted domain influences production traits in domestic livestock, most notably the ovine callipyge phenotype. We assessed genotype-phenotype ...
Control of tnf-induced dendritic cell maturation by hybrid-type n-glycans
(The American Association of Immunologists, 2011-03-21)
The activity of alpha-1,2-mannosidase I is required for the conversion of high-mannose to hybrid-type (ConA reactive) and complex-type N-glycans (Phaseolus vulgaris-leukoagglutinin [PHA-L] reactive) during posttranslational ...
Ulk4 is essential for ciliogenesis and csf flow
(Society for Neuroscience, 2016-07-20)
Ciliopathies are an emerging class of devastating disorders with pleiotropic symptoms affecting both the central and peripheral systems and commonly associated with hydrocephalus. Even though ciliary components and three ...
5-hydroxyethyl-3-tetradecanoyltetramic acid represents a novel treatment for intravascular catheter infections due tostaphylococcus aureus
(Oxford University Press (OUP), 2016-12-20)
Objectives: Biofilm infections of intravascular catheters caused by Staphylococcus aureus may be treated with catheter lock solutions (CLSs). Here we investigated the antibacterial activity, cytotoxicity and CLS potential ...