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Comparison of viral env proteins from acute and chronic infections with subtype c human immunodeficiency virus type 1 identifies differences in glycosylation and ccr5 utilization and suggests a new strategy for immunogen design

Ping, L.-H.; Joseph, S. B.; Anderson, J. A.; Abrahams, M.-R.; Salazar-Gonzalez, J. F.; Kincer, L. P.; Treurnicht, F. K.; Arney, L.; Ojeda, S.; Zhang, M.; Keys, J.; Potter, E. L.; Chu, H.; Moore, P.; Salazar, M. G.; Iyer, S.; Jabara, C.; Kirchherr, J.; Mapanje, C.; Ngandu, N.; Seoighe, C.; Hoffman, I.; Gao, F.; Tang, Y.; Labranche, C.; Lee, B.; Saville, A.; Vermeulen, M.; Fiscus, S.; Morris, L.; Karim, S. A.; Haynes, B. F.; Shaw, G. M.; Korber, B. T.; Hahn, B. H.; Cohen, M. S.; Montefiori, D.; Williamson, C.; Swanstrom, R.; , (American Society for Microbiology, 2013-04-24)

Understanding human immunodeficiency virus type 1 (HIV-1) transmission is central to developing effective prevention strategies, including a vaccine. We compared phenotypic and genetic variation in HIV-1 env genes from ...

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Comparison of viral env proteins from acute and chronic infections with subtype c human immunodeficiency virus type 1 identifies differences in glycosylation and ccr5 utilization and suggests a new strategy for immunogen design