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Evidence for intron length conservation in a set of mammalian genes associated with embryonic development
(Springer Nature, 2011-01-01)
Background: We carried out an analysis of intron length conservation across a diverse group of nineteen mammalian species. Motivated by recent research suggesting a role for time delays associated with intron transcription ...
Insulin-like growth factor (igf) signalling is required for early dorso-anterior development of the zebrafish embryo
(UPV/EHU Press, 2004-01-01)
The insulin-like growth factor (IGF) signalling pathway has been highly conserved in animal evolution and, in mammals and Xenopus, plays a key role in embryonic growth and development, with the IGF-1 receptor (IGF-1R) being ...
Loss of plakophilin 2 disrupts heart development in zebrafish
(UPV/EHU Press, 2012-01-01)
The desmosomal armadillo protein plakophilin 2 is the only plakophilin expressed in the heart, and mutations in the human plakophilin 2 gene result in arrhythmogenic right ventricular cardiomyopathy. To investigate loss ...