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Methyl-cytosine-driven structural changes enhance adduction kinetics of an exon 7 fragment of the p53 gene
(Springer Nature, 2017-01-19)
Methylation of cytosine (C) at C-phosphate-guanine (CpG) sites enhances reactivity of DNA towards electrophiles. Mutations at CpG sites on the p53 tumor suppressor gene that can result from these adductions are in turn ...