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Restriction of human polyomavirus bk virus dna replication in murine cells and extracts

Mahon, C.; Liang, B.; Tikhanovich, I.; Abend, J. R.; Imperiale, M. J.; Nasheuer, Heinz-Peter; Folk, W. R. (American Society for Microbiology, 2009-03-18)

BK virus (BKV) causes persistent and asymptomatic infections in most humans and is the etiologic agent of polyomavirus-associated nephropathy (PVAN) and other pathologies. Unfortunately, there are no animal models with ...

Host-specific replication of bk virus dna in mouse cell extracts is independently controlled by dna polymerase -primase and inhibitory activities

Tikhanovich, I.; Nasheuer, Heinz-Peter (American Society for Microbiology, 2010-04-14)

The activation of the human polyomavirus BK causes polyomavirus-associated nephropathy in immuno-compromised humans. Studies of the virus have been restricted since the virus DNA replication is species specific. Cell-based ...