Search

Now showing items 1-1 of 1

Perk-dependent repression of mir-106b-25 cluster is required for er stress-induced apoptosis

Gupta, S; Read, D E; Deepti, A; Cawley, K; Gupta, A; Oommen, D; Verfaillie, T; Matus, S; Smith, M A; Mott, J L; Agostinis, P; Hetz, C; Samali, A (Springer Nature, 2012-06-01)

Activation of the unfolded protein response sensor PKR-like endoplasmic reticulum kinase (Perk) attenuates endoplasmic reticulum (ER) stress levels. Conversantly, if the damage is too severe and ER function cannot be ...