Now showing items 1-3 of 3
An inherited duplication at the gene p21 protein-activated kinase 7 (pak7) is a risk factor for psychosis
(Oxford University Press (OUP), 2014-01-28)
Identifying rare, highly penetrant risk mutations may be an important step in dissecting the molecular etiology of schizophrenia. We conducted a gene-based analysis of large (&gt; 100 kb), rare copy-number variants ...
A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains
This large multi-center study investigates the relationships between genetic risk for schizophrenia and bipolar disorder, and multi-modal endophenotypes for psychosis. The sample included 4,242 individuals; 1,087 patients ...
The one and the many: effects of the cell adhesion molecule pathway on neuropsychological function in psychosis
(Cambridge University Press (CUP), 2013-11-28)
Background. Genetic studies of single gene variants have been criticized as providing a simplistic characterization of the genetic basis of illness risk that ignores the effects of other variants within the same biological ...