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Cardiopoietic cell therapy for advanced ischemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled chart-1 clinical trial

Bartunek, Jozef; Terzic, Andre; Davison, Beth A.; Filippatos, Gerasimos S.; Radovanovic, Slavica; Beleslin, Branko; Merkely, Bela; Musialek, Piotr; Wojakowski, Wojciech; Andreka, Peter; Horvath, Ivan G.; Katz, Amos; Dolatabadi, Dariouch; El Nakadi, Badih; Arandjelovic, Aleksandra; Edes, Istvan; Seferovic, Petar M.; Obradovic, Slobodan; Vanderheyden, Marc; Jagic, Nikola; Petrov, Ivo; Atar, Shaul; Halabi, Majdi; Gelev, Valeri L.; Shochat, Michael K.; Kasprzak, Jaroslaw D.; Sanz-Ruiz, Ricardo; Heyndrickx, Guy R.; Nyolczas, Noémi; Legrand, Victor; Guédès, Antoine; Heyse, Alex; Moccetti, Tiziano; Fernandez-Aviles, Francisco; Jimenez-Quevedo, Pilar; Bayes-Genis, Antoni; Hernandez-Garcia, Jose Maria; Ribichini, Flavio; Gruchala, Marcin; Waldman, Scott A.; Teerlink, John R.; Gersh, Bernard J.; Povsic, Thomas J.; Henry, Timothy D.; Metra, Marco; Hajjar, Roger J.; Tendera, Michal; Behfar, Atta; Alexandre, Bertrand; Seron, Aymeric; Stough, Wendy Gattis; Sherman, Warren; Cotter, Gad; Wijns, William; , (Oxford University Press (OUP), 2016-12-23)

Aims Cardiopoietic cells, produced through cardiogenic conditioning of patients' mesenchymal stem cells, have shown preliminary efficacy. The Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) trial aimed ...

Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the lung safe prospective cohort study

Laffey, John G; Madotto, Fabiana; Bellani, Giacomo; Pham, Tài; Fan, Eddy; Brochard, Laurent; Amin, Pravin; Arabi, Yaseen; Bajwa, Ednan K; Bruhn, Alejandro; Cerny, Vladimir; Clarkson, Kevin; Heunks, Leo; Kurahashi, Kiyoyasu; Laake, Jon Henrik; Lorente, Jose A; McNamee, Lia; Nin, Nicolas; Palo, Jose Emmanuel; Piquilloud, Lise; Qiu, Haibo; Jiménez, Juan Ignacio Silesky; Esteban, Andres; McAuley, Daniel F; van Haren, Frank; Ranieri, Marco; Rubenfeld, Gordon; Wrigge, Hermann; Slutsky, Arthur S; Pesenti, Antonio (Elsevier BV, 2017-08-01)

Background Little information is available about the geo-economic variations in demographics, management, and outcomes of patients with acute respiratory distress syndrome (ARDS). We aimed to characterise the effect of ...

Urinary sodium and potassium excretion and risk of cardiovascular events

O'Donnell, Martin J.; Yusuf, Salim; Mente, Andrew; Gao, Peggy; Mann, Johannes F.; Teo, Koon; McQueen, Matthew; Sleight, Peter; Sharma, Arya M.; Dans, Antonio; Probstfield, Jeffrey; Schmieder, Roland E. (American Medical Association (AMA), 2011-11-23)

Context The precise relationship between sodium and potassium intake and cardiovascular (CV) risk remains uncertain, especially in patients with CV disease. Objective To determine the association between estimated urinary ...

Using pm2.5 concentrations to estimate the health burden from solid fuel combustion, with application to irish and scottish homes

Galea, Karen S; Hurley, J Fintan; Cowie, Hilary; Shafrir, Amy L; Sánchez Jiménez, Araceli; Semple, Sean; Ayres, Jon G; Coggins, Marie (Springer Nature, 2013-06-19)

Background: This study estimates the potential population health burden from exposure to combustion-derived particulate air pollution in domestic settings in Ireland and Scotland. Methods: The study focused on solid fuel ...

Cognitive impairment and risk of cardiovascular events and mortality

O'Donnell, M.; Teo, K.; Gao, P.; Anderson, C.; Sleight, P.; Dans, A.; Marzona, I.; Bosch, J.; Probstfield, J.; Yusuf, S. (Oxford University Press (OUP), 2012-05-02)

Cognitive impairment may increase the risk of all cardiovascular (CV) events. We prospectively evaluated the independent association between Mini-Mental State Examination (MMSE) score and myocardial infarction, stroke, ...

Determinants of respirable crystalline silica exposure among stoneworkers involved in stone restoration work

Unknown author (Oxford University Press (OUP), 2013-08-31)

Objectives: Crystalline silica occurs as a significant component of many traditional materials used in restoration stonework, and stoneworkers who work with these materials are potentially exposed to stone dust containing ...

Effectiveness of a smartphone application to promote physical activity in primary care: the smart move randomised controlled trial

Glynn, L. G.; Hayes, P. S.; Casey, M.; Glynn, F.; Alvarez-Iglesias, A.; Newell, J.; OLaighin, G.; Heaney, D.; O'Donnell, M.; Murphy, A. W. (Royal College of General Practitioners, 2014-06-30)

Background Physical inactivity is a major, potentially modifiable, risk factor for cardiovascular disease, cancer, and other chronic diseases. Effective, simple, and generalisable interventions that will increase physical ...