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Micrornas as prognostic indicators and therapeutic targets: potential effect on breast cancer management
(American Association for Cancer Research (AACR), 2008-01-15)
The discovery of microRNAs (miRNA) as novel modulators of gene expression has resulted in a rapidly expanding repertoire of molecules in this family, as reflected in the concomitant expansion of scientific literature. ...
Trigger factor from the psychrophilic bacterium psychrobacter frigidicola is a monomeric chaperone
(American Society for Microbiology, 2008-12-05)
In eubacteria, trigger factor (TF) is the first chaperone to interact with newly synthesized polypeptides and assist their folding as they emerge from the ribosome. We report the first characterization of a TF from a ...
Otolith shape analysis: its application for discriminating between stocks of irish sea and celtic sea herring (clupea harengus) in the irish sea
(Oxford University Press (OUP), 2008-12-01)
The extensive movement of Celtic Sea juvenile Atlantic herring (Clupea harengus) during the first year of life into the Irish Sea results in two stocks of herring living together on Irish Sea nursery grounds: the resident ...
Integrated microfluidic tmrna purification and real-time nasba device for molecular diagnostics
(Royal Society of Chemistry (RSC), 2008-01-01)
We demonstrate the first integrated microfluidic tmRNA purification and nucleic acid sequence-based amplification (NASBA) device incorporating real-time detection. The real-time amplification and detection step produces ...
Growth arrest-specific gene 6 expression in human breast cancer
(Springer Nature, 2008-02-19)
Growth arrest- specific gene 6 ( Gas6), identified in 1995, acts as the ligand to the Axl/ Tyro3 family of tyrosine kinase receptors and exerts mitogenic activity when bound to these receptors. Overexpression of the Axl/ ...
Extended visual simultaneity thresholds in patients with schizophrenia
(Oxford University Press (OUP), 2008-03-21)
Clinical observations suggest that the experience of time phenomenology is disturbed in schizophrenia, possibly originating disorders in dynamic cognitive functions such as language or motor planning. We examined the ...
Prevalence and numbers ofsalmonellaspp. and enterobacteriaceae on pork cuts in abattoirs in the republic of ireland
(Wiley-Blackwell, 2008-10-01)
Aims: This study aimed to determine the numbers and types of Salmonella spp. and Enterobacteriaceae on pork cuts in the meat cutting room environment of four commercial pork abattoirs in the Republic of Ireland.
Methods ...
Psp toxin analysis and discrimination of the naturally co-occurring alexandrium tamarense and a. minutum (dinophyceae) in cork harbour, ireland
(Inter-Research Science Center, 2008-06-16)
A mixed community composed of a non-toxic form of Alexandrium tamarense and a paralytic shellfish poisoning (PSP) toxin-producing A. minutum develops on an annual basis in Cork Harbour, Ireland. The understanding of the ...
Development of a real-time multiplex pcr assay for the detection of multiple salmonella serotypes in chicken samples
(Springer Nature, 2008-01-01)
Background: A real-time multiplex PCR assay was developed for the detection of multiple Salmonella serotypes in chicken samples. Poultry-associated serotypes detected in the assay include Enteritidis, Gallinarum, Typhimurium, ...