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Compartmental oxidation of thiol–disulphide redox couples during epidermal growth factor signalling
(Portland Press Ltd., 2005-03-01)
Exogenously added ROS (reactive oxygen species) cause generalized oxidation of cellular components, whereas endogenously generated ROS induced by physiological stimuli activate discrete signal transduction pathways. ...
Chemical structures of the core regions of campylobacter jejuni serotypes o:1, o:4, o:23, and o:36 lipopolysaccharides
(Wiley-Blackwell, 1993-05-01)
Complete structures, including the location of N-acetylneuraminic acid (Neu5Ac) residues, were assigned for the core regions of Campylobacter jejuni serotypes 0:1, 0:4, and 0:23 and 0:36 lipopolysaccharides (LPS). In ...
Insulin-like growth factor (igf) signalling is required for early dorso-anterior development of the zebrafish embryo
(UPV/EHU Press, 2004-01-01)
The insulin-like growth factor (IGF) signalling pathway has been highly conserved in animal evolution and, in mammals and Xenopus, plays a key role in embryonic growth and development, with the IGF-1 receptor (IGF-1R) being ...
Lewis x structures in the o antigen side-chain promote adhesion of helicobacter pylori to the gastric epithelium
(Wiley-Blackwell, 2002-01-18)
Helicobacter pylori NCTC11637 expresses a lipopolysaccharide (LPS) that comprises an O antigen side-chain with structural homology to the human blood group antigen Lewis X (Le(x)). The role of this molecule in adhesion of ...
Role of listeria monocytogenes b in survival of lethal acidic conditions and in the acquired acid tolerance response
(American Society for Microbiology, 2003-05-01)
The food-borne pathogen Listeria monocytogenes can acquire enhanced resistance to lethal acid conditions through multiple mechanisms. We investigated contributions of the stress-responsive alternative sigma factor, or ...
Specific pgf2αreceptor (fp) antagonism and human uterine contractilityin vitro
(Wiley-Blackwell, 2005-08-01)
Objective PGF(2 alpha) acts through its receptor, FP, as an important smooth muscle contractile agent. The aim of this study was to investigate the effects of specific FP antagonism, using the novel-specific FP non-competitive ...
Global effects of homocysteine on transcription in escherichia coli: induction of the gene for the major cold-shock protein, cspa
(Microbiology Society, 2006-08-01)
Homocysteine (Hey) is a thiol-containing amino acid that is considered to be medically important because it is linked to the development of several life-threatening diseases in humans, including cardiovascular disease and ...
Mutations in the genes for oocyte-derived growth factors gdf9 and bmp15 are associated with both increased ovulation rate and sterility in cambridge and belclare sheep (ovis aries)1
(Oxford University Press (OUP), 2004-04-01)
Belclare and Cambridge are prolific sheep breeds, the origins of which involved selecting ewes with exceptionally high litter size records from commercial flocks. The variation in ovulation rate in both breeds is consistent ...
Relationship of anti-lewis x and anti-lewis y antibodies in serum samples from gastric cancer and chronic gastritis patients to helicobacter pylori-mediated autoimmunity
(American Society for Microbiology, 2001-08-01)
Lewis (Le) antigens have been implicated in the pathogenesis of atrophic gastritis and gastric cancer in the setting of Helicobacter pylori infection, and H. pylori-induced anti-Le antibodies have been described that ...
The fate of foreign dna associated with pig sperm following the in vitro fertilization of zona-free hamster ova and zona-intact pig ova
(Informa UK Limited, 1992-01-01)
The aim of this study was to determine the fate of foreign DNA molecules bound to porcine sperm that had been capacitated and acrosome reacted in vitro using calcium ionophore and then used in the in vitro fertilization ...