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Characterizing the diverse mutational pathways associated with r5-tropic maraviroc resistance: hiv-1 that uses the drug-bound ccr5 coreceptor
(American Society for Microbiology, 2015-09-02)
Entry inhibitors represent a potent class of antiretroviral drugs that target a host cell protein, CCR5, an HIV-1 entry coreceptor, and not viral protein. Lack of sensitivity can occur due to preexisting virus that uses ...