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Mesenchymal stem cell inhibition of t-helper 17 cell- differentiation is triggered by cell-cell contact and mediated by prostaglandin e2 via the ep4 receptor

Duffy, Michelle M.; Pindjakova, Jana; Hanley, Shirley A.; McCarthy, Cathal; Weidhofer, Gudrun A.; Sweeney, Eva M.; English, Karen; Shaw, Georgina; Murphy, J. Mary; Barry, Frank P.; Mahon, Bernard P.; Belton, Orina; Ceredig, Rhodri; Griffin, Matthew D. (Wiley-Blackwell, 2011-08-30)

Mesenchymal stem cells (MSCs) inhibit T-cell activation and proliferation but their effects on individual T-cell-effector pathways and on memory versus naive T cells remain unclear. MSC influence on the differentiation of ...