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Plakoglobin has both structural and signalling roles in zebrafish development
(Elsevier BV, 2009-03-01)
Insulin-like growth factor (igf) signalling is required for early dorso-anterior development of the zebrafish embryo
(UPV/EHU Press, 2004-01-01)
The insulin-like growth factor (IGF) signalling pathway has been highly conserved in animal evolution and, in mammals and Xenopus, plays a key role in embryonic growth and development, with the IGF-1 receptor (IGF-1R) being ...
Evidence for intron length conservation in a set of mammalian genes associated with embryonic development
(Springer Nature, 2011-01-01)
Background: We carried out an analysis of intron length conservation across a diverse group of nineteen mammalian species. Motivated by recent research suggesting a role for time delays associated with intron transcription ...
Plakoglobin expression and localization in zebrafish embryo development
(Portland Press Ltd., 2004-11-01)
Plakoglobin (gamma-catenin) and beta-catenin are major components of the adherens junctions and can be localized to the nucleus by activation of the Wnt signalling pathway. In addition, plakoglobin is also found in desmosomes, ...
Loss of plakophilin 2 disrupts heart development in zebrafish
(UPV/EHU Press, 2012-01-01)
The desmosomal armadillo protein plakophilin 2 is the only plakophilin expressed in the heart, and mutations in the human plakophilin 2 gene result in arrhythmogenic right ventricular cardiomyopathy. To investigate loss ...
Insulin-like growth factor-2 regulates early neural and cardiovascular system development in zebrafish embryos
(UPV/EHU Press, 2010-01-01)
The insulin-like growth factor (IGF) family is essential for normal embryonic growth and development and it is highly conserved through vertebrate evolution. However, the roles that the individual members of the IGF family ...