Now showing items 1-3 of 3
Biological activities of lipopolysaccharides are determined by the shape of their lipid a portion
Lipopolysaccharide (LPS) represents a major virulence factor of Gram-negative bacteria ('endotoxin') that can cause septic shock in mammals including man. The lipid anchor of LPS to the outer membrane, lipid A, has a ...
Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling
(American Chemical Society (ACS), 2013-01-07)
The coprocessing of active pharmaceutical ingredient (API) with an excipient which has a high glass transition temperature (T-g) is a recognized strategy to stabilize the amorphous form of a drug. This work investigates ...
Effect of microfibril twisting on theoretical powder diffraction patterns of cellulose iβ
(Springer Nature, 2013-09-25)
Previous studies of calculated diffraction patterns for cellulose crystallites suggest that distortions that arise once models have been subjected to molecular dynamics (MD) simulation are the result of both microfibril ...