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Parp-1 protects homologous recombination from interference by ku and ligase iv in vertebrate cells
(Wiley-Blackwell, 2006-02-23)
Parp-1 and Parp-2 are activated by DNA breaks and have been implicated in the repair of DNA single-strand breaks (SSB). Their involvement in double-strand break (DSB) repair mediated by homologous recombination (HR) or ...
Dn2 thymocytes activate a specific robust dna damage response to ionizing radiation-induced dna double-strand breaks
(Frontiers Media SA, 2018-06-11)
For successful bone marrow transplantation (BMT), a preconditioning regime involving chemo and radiotherapy is used that results in DNA damage to both hematopoietic and stromal elements. Following radiation exposure, it ...