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Yeast histone 2a serine 129 is essential for the efficient repair of checkpoint-blind dna damage
Cells maintain genomic stability by the coordination of DNA-damage repair and cell-cycle checkpoint control. In replicating cells, DNA damage usually activates intra-S-phase checkpoint controls, which are characterized by ...
Dna-pk activity is associated with caspase-dependent myogenic differentiation
Differentiation of myoblasts into myotubes is essential for skeletal muscle development and regeneration. Caspase-3 and caspase-9 are required for efficient myoblast differentiation. The caspase-activated endonuclease ...
Co-mutation of histone h2ax s139a with y142a rescues y142a-induced ionising radiation sensitivity