Now showing items 1-2 of 2
Mirna signature of unfolded protein response in h9c2 rat cardiomyoblasts
(Springer Nature, 2014-01-01)
Background: Glucose and oxygen deprivation during ischemia is known to affect the homeostasis of the endoplasmic reticulum (ER) in ways predicted to activate the unfolded protein response (UPR). Activation of UPR signalling ...
Perk-dependent repression of mir-106b-25 cluster is required for er stress-induced apoptosis
(Springer Nature, 2012-06-01)
Activation of the unfolded protein response sensor PKR-like endoplasmic reticulum kinase (Perk) attenuates endoplasmic reticulum (ER) stress levels. Conversantly, if the damage is too severe and ER function cannot be ...