Now showing items 1-2 of 2
Heritability in the efficiency of nonsense-mediated mrna decay in humans
(Public Library of Science (PLoS), 2010-07-21)
Background: In eukaryotes mRNA transcripts of protein-coding genes in which an intron has been retained in the coding region normally result in premature stop codons and are therefore degraded through the nonsense-mediated ...
Mirna signature of unfolded protein response in h9c2 rat cardiomyoblasts
(Springer Nature, 2014-01-01)
Background: Glucose and oxygen deprivation during ischemia is known to affect the homeostasis of the endoplasmic reticulum (ER) in ways predicted to activate the unfolded protein response (UPR). Activation of UPR signalling ...