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Endoplasmic reticulum stress-mediated induction of sestrin 2 potentiates cell survival
(Impact Journals, LLC, 2016-02-22)
Upregulation of SESTRIN 2 (SESN2) has been reported in response to diverse cellular stresses. In this study we demonstrate SESTRIN 2 induction following endoplasmic reticulum (ER) stress. ER stress-induced increases in ...
Trail receptor gene editing unveils trail-r1 as a master player of apoptosis induced by trail and er stres
(Impact Journals, LLC, 2016-12-27)
TRAIL induces selective tumor cell death through TRAIL-R1 and TRAIL-R2. Despite the fact that these receptors share high structural homologies, induction of apoptosis upon ER stress, cell autonomous motility and invasion ...