Now showing items 1-4 of 4
Dna-pk activity is associated with caspase-dependent myogenic differentiation
Differentiation of myoblasts into myotubes is essential for skeletal muscle development and regeneration. Caspase-3 and caspase-9 are required for efficient myoblast differentiation. The caspase-activated endonuclease ...
Hucop1 contributes to the regulation of dna repair in keratinocytes
(Springer Nature, 2016-12-19)
We have previously demonstrated that the E3 ligase Human Constitutive Photomorphogenic Protein (huCOP1) is expressed in human keratinocytes and negatively regulates p53. The MutS homolog 2 (MSH2) protein plays a central ...
Cep164-null cells generated by genome editing show a ciliation defect with intact dna repair capacity
(The Company of Biologists, 2016-03-10)
Primary cilia are microtubule structures that extend from the distal end of the mature, mother centriole. CEP164 is a component of the distal appendages carried by the mother centriole that is required for primary cilium ...
Multi-scale modelling of rubber-like materials and soft tissues:an appraisal
(The Royal Society, 2016-03-01)
We survey, in a partial way, multi-scale approaches for the modelling of rubber-like and soft tissues and compare them with classical macroscopic phenomenological models. Our aim is to show how it is possible to obtain ...