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Hydroxymethylglutaryl-coa reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (harp-2) trial: study protocol for a randomized controlled trial
(Springer Nature, 2012-09-17)
Background: Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure. There are in vitro, animal ...
Simvastatin in the acute respiratory distress syndrome
(New England Journal of Medicine (NEJM/MMS), 2014-10-30)
BACKGROUND
Studies in animals and in vitro and phase 2 studies in humans suggest that statins may be beneficial in the treatment of the acute respiratory distress syndrome (ARDS). This study tested the hypothesis that ...
Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the world society of the abdominal compartment syndrome
(Springer Nature, 2013-05-15)
To update the World Society of the Abdominal Compartment Syndrome (WSACS) consensus definitions and management statements relating to intra-abdominal hypertension (IAH) and the abdominal compartment syndrome (ACS).
We ...