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Constitutive activation of ectodermal β-catenin induces ectopic outgrowths at various positions in mouse embryo and affects abdominal ventral body wall closure
(Public Library of Science (PLoS), 2014-03-19)
Vertebrate limbs originate from the lateral plate mesoderm (LPM) and the overlying ectoderm. While normal limb formation in defined regions has been well studied, the question of whether other positions retain limb-forming ...
Overexpression of wnt5a in mouse epidermis causes no psoriasis phenotype but an impairment of hair follicle anagen development
(Wiley-Blackwell, 2014-10-10)
Increased Wnt5a expression has been observed in psoriatic plaques. However, whether Wnt5a overexpression directly causes psoriasis is unknown. In this study, we generated transgenic (TG) mice with epidermal Wnt5a overexpression ...