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    • Oxytocic plant cyclotides as templates for peptide g protein-coupled receptor ligand design 

      Koehbach, J.; O'Brien, M.; Muttenthaler, M.; Miazzo, M.; Akcan, M.; Elliott, A. G.; Daly, N. L.; Harvey, P. J.; Arrowsmith, S.; Gunasekera, S.; Smith, T. J.; Wray, S.; Goransson, U.; Dawson, P. E.; Craik, D. J.; Freissmuth, M.; Gruber, C. W. (Proceedings of the National Academy of Sciences, 2013-11-18)
      Cyclotides are plant peptides comprising a circular backbone and three conserved disulfide bonds that confer them with exceptional stability. They were originally discovered in Oldenlandia affinis based on their use in ...