Show simple item record

dc.contributor.authorToh, G.W.-L.
dc.contributor.authorLowndes, N.F.
dc.date.accessioned2018-08-24T08:26:32Z
dc.date.available2018-08-24T08:26:32Z
dc.date.issued2003-02-01
dc.identifier.citationToh, G.W.-L. Lowndes, N.F. (2003). Role of the saccharomyces cerevisiae rad9 protein in sensing and responding to dna damage. Biochemical Society Transactions 31 , 242-246
dc.identifier.issn0300-5127,1470-8752
dc.identifier.urihttp://hdl.handle.net/10379/9936
dc.description.abstractEukaryotic cells have evolved surveillance mechanisms, known as DNA-damage checkpoints, that sense and respond to genome damage. DNA-damage checkpoint pathways ensure co-ordinated cellular responses to DNA damage, including cell cycle delays and activation of repair mechanisms. RAD9, from Saccharomyces cerevisiae, was the first damage checkpoint gene to be identified, although its biochemical function remained unknown until recently. This review examines briefly work that provides significant insight into how Rad9 activates the checkpoint signalling kinase Rad53.
dc.publisherPortland Press Ltd.
dc.relation.ispartofBiochemical Society Transactions
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Ireland
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/
dc.subjectcell cycle
dc.subjectprotein phosphorylation
dc.subjectprotein serine/threonine kinase
dc.subjectbudding yeast rad9
dc.subjectcell-cycle
dc.subjectreplication checkpoint
dc.subjectfha domain
dc.subjectin-vivo
dc.subjects-phase
dc.subjectphosphorylation
dc.subjectbrca1
dc.subjectatm
dc.subjectpathways
dc.titleRole of the saccharomyces cerevisiae rad9 protein in sensing and responding to dna damage
dc.typeArticle
dc.identifier.doi10.1042/bst0310242
dc.local.publishedsourcehttp://www.biochemsoctrans.org/content/ppbiost/31/1/242.full.pdf
nui.item.downloads0


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 Ireland
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Ireland