dc.contributor.author | Nachamkin, I. | |
dc.contributor.author | Liu, J. | |
dc.contributor.author | Li, M. | |
dc.contributor.author | Ung, H. | |
dc.contributor.author | Moran, A. P. | |
dc.contributor.author | Prendergast, M. M. | |
dc.contributor.author | Sheikh, K. | |
dc.date.accessioned | 2018-08-24T08:25:50Z | |
dc.date.available | 2018-08-24T08:25:50Z | |
dc.date.issued | 2002-09-01 | |
dc.identifier.citation | Nachamkin, I. Liu, J.; Li, M.; Ung, H.; Moran, A. P.; Prendergast, M. M.; Sheikh, K. (2002). Campylobacter jejuni from patients with guillain-barre syndrome preferentially expresses a gd1a-like epitope. Infection and Immunity 70 (9), 5299-5303 | |
dc.identifier.issn | 0019-9567 | |
dc.identifier.uri | http://hdl.handle.net/10379/9617 | |
dc.description.abstract | GM(1)- and GD(1a)-like ganglioside mimicry in Campylobacter jejuni lipooligosaccharide (LOS) is considered to be involved in the pathogenesis of Campylobacter-induced Guillain-Barre syndrome (GBS). Compared with gastroenteritis-related isolates, GBS-related C. jejuni isolates were strongly associated with the expression of GDla-like mimicry. The presence of a few genes involved in LOS ganglioside mimicry, cst-II, cgtA, and cgtB, was also associated with GBS-related strains. GDla like epitope expression may be an important virulence phenotype associated with the risk of developing GBS following campylobacter infection. | |
dc.publisher | American Society for Microbiology | |
dc.relation.ispartof | Infection and Immunity | |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Ireland | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/ie/ | |
dc.subject | molecular mimicry | |
dc.subject | lipo-oligosaccharide | |
dc.subject | helicobacter-pylori | |
dc.subject | anti-gd1a antibody | |
dc.subject | gm1 ganglioside | |
dc.subject | lipopolysaccharides | |
dc.subject | gastroenteritis | |
dc.subject | infections | |
dc.subject | serotypes | |
dc.subject | strains | |
dc.title | Campylobacter jejuni from patients with guillain-barre syndrome preferentially expresses a gd1a-like epitope | |
dc.type | Article | |
dc.identifier.doi | 10.1128/iai.70.9.5299-5303.2002 | |
dc.local.publishedsource | http://iai.asm.org/content/70/9/5299.full.pdf | |
nui.item.downloads | 0 | |