Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ω-allylic amine

Heaney, Frances; Bourke, Sharon; Burke, Cathriona; Cunningham, Desmond; McArdle, Patrick

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1998-01-01

Author

Heaney, Frances

Bourke, Sharon

Burke, Cathriona

Cunningham, Desmond

McArdle, Patrick

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Heaney, Frances; Bourke, Sharon; Burke, Cathriona; Cunningham, Desmond; McArdle, Patrick (1998). Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ω-allylic amine. Journal of the Chemical Society, Perkin Transactions 1 (15), 2255-2257

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http://eprints.maynoothuniversity.ie/7969/7/FH-Preparation-imidazo-1998.pdf

Abstract

Synthesis of the title ring system by a sequential intermolecular nucleophilic displacement and intramolecular 'conjugate' addition has been achieved both as a one pot and as a stepwise procedure; an X-ray structure determination has been carried out to distinguish between the possible isomeric structures 8c-I and 8c-II.

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http://hdl.handle.net/10379/9278

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