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Analysis of Maxi-K alpha subunit splice variants in human myometrium
(springer, 2004-09-21)
Background: Large-conductance, calcium-activated potassium (Maxi-K) channels are implicated
in the modulation of human uterine contractions and myometrial Ca2+ homeostasis. However, the
regulatory mechanism(s) governing ...
Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin
(BioMed Central, 2009-01-08)
Background: Preterm labour occurs in approximately 10% of pregnancies and is a major cause of infant morbidity and mortality. However, the pathways involved in regulating contractility in normal and preterm labour are not ...
Decreased myometrial p160 ROCK-1 expression in obese women at term pregnancy
(2013)
Background: Obesity is becoming an increasing problem in obstetric practice; it has led to an increase in the risk of caesarean delivery, prolonged pregnancy and dysfunctional labour. It has been postulated that many of ...
Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction
(Society for Reproduction and Fertility, 2006-07-01)
Pre eclampsia represents a state of increased or prolonged vasoconstriction, partially linked to the potent vasocontractile effect of isoprostanes. The process of Rho A-mediated calcium sensitisation is inherent to a state ...