dc.contributor.author | McDermott, Barry | |
dc.contributor.author | Porter, Emily | |
dc.contributor.author | Jones, Marggie | |
dc.contributor.author | McGinley, Brian | |
dc.contributor.author | O'Halloran, Martin | |
dc.date.accessioned | 2018-08-20T10:33:56Z | |
dc.date.issued | 2018-04-26 | |
dc.identifier.citation | McDermott, Barry, Porter, Emily, Jones, Marggie, McGinley, Brian, & O'Halloran, Martin. (2018). Symmetry difference electrical impedance tomography-a novel modality for anomaly detection. Physiological Measurement 39(4). doi: 10.1088/1361-6579/aab656 | en_IE |
dc.identifier.issn | 0967-3334 | |
dc.identifier.uri | http://hdl.handle.net/10379/7513 | |
dc.description.abstract | Objective: The theoretical basis, experimental implementation, and proof of concept of a novel electrical impedance tomography (EIT) imaging technique, called symmetry difference EIT, is described. This technique is applicable in situations where there is inherent symmetry in the region being imaged. Methods: The sample scenario of the human head is used to describe the technique. The head is largely symmetrical across the sagittal plane. A unilateral lesion such as a haemorrhage or region of ischaemia distorts that symmetry. This distortion may be visualised using EIT. Measurement sets from a ring of electrodes placed on the boundary in both clockwise and counter-clockwise orientations are compared to detect the anomaly. Computer simulations featuring a hemispherical model of the head and brain are used initially to demonstrate the theory. Then, a more complex numerical model with anatomically accurate finite element models (FEMs) is used to expand on the concept with a more realistic scenario. Finally, tank experiments are performed with phantom lesions to validate the technique in the real world. Results: Deviations from normal symmetry, due to the presence of lesions, are detectable using this new modality. The ease of detection improves with larger lesions and those far from the plane of symmetry. Quantitative metrics, as well as an image, help to robustly detect and identify both the presence of an abnormality and the cause (haemorrhagic or ischaemic lesion in the scenarios tested) or indeed indicate where no detection is possible. Conclusion: Symmetry difference EIT is a valuable new modality that is applicable to cases where the 'normal' features symmetry across a plane. Significantly, a change in the region of interest is not required and hence this technique may be suited to static or quasi-static cases where time difference EIT cannot be used. | en_IE |
dc.description.sponsorship | The research leading to these results has received funding from the European Research Council under the European Union's Horizon 2020 Programme/ERC Grant Agreement BioElecPro n.637780, Science Foundation Ireland (SFI) grant number 15/ERCS/3276, the Hardiman Research Scholarship from NUIG, the charity RESPECT and the People Programme (Marie Curie Actions) of the European Union's Seventh Framework Programme (FP7/2007-2013) under REA Grant Agreement no. PCOFUND-GA-2013-608728. | en_IE |
dc.format | application/pdf | en_IE |
dc.language.iso | en | en_IE |
dc.publisher | IOP Publishing | en_IE |
dc.relation.ispartof | Physiological Measurement | en |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Ireland | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/3.0/ie/ | |
dc.subject | FINITE-ELEMENT MESHES | en_IE |
dc.subject | INTRACEREBRAL HEMORRHAGE | en_IE |
dc.subject | ACUTE STROKE | en_IE |
dc.subject | HUMAN HEAD | en_IE |
dc.subject | EIT | en_IE |
dc.subject | ACCURATE | en_IE |
dc.subject | DISEASE | en_IE |
dc.subject | IMAGES | en_IE |
dc.title | Symmetry difference electrical impedance tomography-a novel modality for anomaly detection | en_IE |
dc.type | Article | en_IE |
dc.date.updated | 2018-08-15T17:14:39Z | |
dc.identifier.doi | 10.1088/1361-6579/aab656 | |
dc.local.publishedsource | https://dx.doi.org/10.1088/1361-6579/aab656 | en_IE |
dc.description.peer-reviewed | peer-reviewed | |
dc.contributor.funder | Science Foundation Ireland | en_IE |
dc.contributor.funder | European Research Council | en_IE |
dc.contributor.funder | Horizon 2020 | en_IE |
dc.contributor.funder | FP7 People: Marie-Curie Actions | en_IE |
dc.contributor.funder | Hardiman Research Scholarship, NUI Galway | |
dc.contributor.funder | RESPECT | |
dc.description.embargo | 2019-04-26 | |
dc.internal.rssid | 14792798 | |
dc.local.contact | Barry Mc Dermott, Translational Medical Device Lab, , 2nd Floor Lambe Translational Research Facility,, University College Hospital, , Galway. - Email: b.mcdermott3@nuigalway.ie | |
dc.local.copyrightchecked | Yes | |
dc.local.version | ACCEPTED | |
dcterms.project | info:eu-repo/grantAgreement/SFI/SFI ERC Support Programme/15/ERCS/3276/IE/BIOELECPRO: Frontier Research on the Dielectric Properties of Biological Tissue/ | en_IE |
dcterms.project | info:eu-repo/grantAgreement/EC/H2020::ERC::ERC-STG/637780/EU/Frontier Research on the Dielectric Properties of Biological Tissue/BIOELECPRO | en_IE |
nui.item.downloads | 277 | |