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In vivo correlation mapping microscopy
(Society of Photo-optical Instrumentation Engineers (SPIE), 2016-03)
To facilitate regular assessment of the microcirculation in vivo, noninvasive imaging techniques such as nailfold capillaroscopy are required in clinics. Recently, a correlation mapping technique has been applied to optical ...
Investigation of nanoscale structural alterations of cell nucleus as an early sign of cancer
(BioMed Central, 2014)
Background: The cell and tissue structural properties assessed with a conventional bright-field light microscope play a key role in cancer diagnosis, but they sometimes have limited accuracy in detecting early-stage cancers ...
Novel approach for label free super-resolution imaging in far field
(Nature Publishing Group, 2015)
Progress in the emerging areas of science and technology, such as bio- and nano-technologies,
depends on development of corresponding techniques for imaging and probing the structures with
high resolution. Recently, the ...
Nano-sensitive optical coherence tomography
(Royal Society of Chemistry, 2014)
Depth resolved label-free detection of structural changes with nanoscale sensitivity is an outstanding problem in the biological and physical sciences and has significant applications in both the fundamental research and ...
Investigation of depth-resolved nanoscale structural changes in regulated cell proliferation and chromatin decondensation
(2013)
We present depth-resolved spatial-domain low-coherence quantitative phase microscopy, a simple approach that utilizes coherence gating to construct a depth-resolved structural feature vector quantifying sub-resolution axial ...
Performance review of multiple reference versus time domain optical coherence tomography
(IEEE, 2018-04-19)
We present a detailed characterization of noise sources in multiple reference optical coherence tomography (MR-OCT) compared to time-domain OCT (TD-OCT). The noise characteristics were modeled based on the TD-OCT noise ...
Nanosensitive optical coherence tomography for the study of changes in static and dynamic structures
(IOP Science, 2014-03-06)
We briefly discuss the principle of image formation in Fourier domain optical coherence tomography (OCT). The theory of a new approach to improve dramatically the sensitivity of conventional OCT is described. The approach ...
Spatial frequency domain correlation mapping optical coherence tomography for nanoscale structural characterization
(AIP Publishing, 2019-09-16)
Most of the fundamental pathological processes in living tissues exhibit changes at the nanoscale. Noninvasive, label-free detection of structural changes in biological samples pose a significant challenge to both researchers ...
Label-free ultra-sensitive visualization of structure below the diffraction resolution limit
(Wiley, 2018-03-23)
For both fundamental study of biological processes and early diagnosis of diseases, information about nanoscale changes in tissue and cell structure is crucial. Nowadays, almost all currently known nanoscopy methods rely ...
Simultaneous en-face imaging of multiple layers with multiple reference optical coherence tomography
(Society of Photo-optical Instrumentation Engineers, 2017-08-22)
A technique based on multiple reference optical coherence tomography (MR-OCT) is proposed for simultaneous imaging at multiple depths. The technique has been validated by imaging a reference sample and a fingerprint in-vivo. ...