Now showing items 1-4 of 4

    • In vivo correlation mapping microscopy 

      McGrath, James; Alexandrov, Sergey; Owens, Peter; Subhash, Hrebesh; Leahy, Martin (Society of Photo-optical Instrumentation Engineers (SPIE), 2016-03)
      To facilitate regular assessment of the microcirculation in vivo, noninvasive imaging techniques such as nailfold capillaroscopy are required in clinics. Recently, a correlation mapping technique has been applied to optical ...
    • Label free ultra-sensitive imaging with sub-diffraction spatial resolution 

      Alexandrov, Sergey; Das, Nandan; McGrath, James; Owens, Peter; Sheppard, Colin J. R.; Boccafoschi, Francesca; Giannini, Cinzia; Sibillano, Teresa; Subhash, Hrebesh; Leahy, Martin (IEEE, 2019-07-09)
      In this paper, we show a new way to break the resolution limit and dramatically improve sensitivity to structural changes. To realize it we developed a novel label free contrast mechanism, based on the spectral encoding ...
    • Novel approach for label free super-resolution imaging in far field 

      Alexandrov, Sergey; McGrath, James; Hrebesh, Subhash; Leahy, Martin (Nature Publishing Group, 2015)
      Progress in the emerging areas of science and technology, such as bio- and nano-technologies, depends on development of corresponding techniques for imaging and probing the structures with high resolution. Recently, the ...
    • Ultra-sensitive label free imaging below the resolution limit 

      Alexandrov, Sergey; McGrath, James; Sheppard, Colin J. R.; Boccafoschi, Francesca; Giannini, Cinzia; Sibillano, Teresa; Subhash, Hrebesh; Hogan, Josh; Leahy, James J. (SPIE (Society of Photo-optical Instrumentation Engineers) Digital Library, 2019-02-02)
      Almost all known nanoscopy methods rely upon the contrast created by fluorescent labels attached to the object of interest. This causes limitations on their applicability to in vivo imaging. A new label-free spectral ...