Now showing items 1-5 of 5
Encapsulation of primary dopaminergic neurons in a GDNF-loaded collagen hydrogel increases their survival, re-innervation and function after intra-striatal transplantation
(Nature Research, 2017-11-22)
Poor graft survival limits the use of primary dopaminergic neurons for neural repair in Parkinson's disease. Injectable hydrogels have the potential to significantly improve the outcome of such reparative approaches by ...
Brain repair for Parkinson's disease: is the answer in the matrix?
(Medknow Publications, 2018-07-13)
Two hundred years after James Parkinson first described the cardinal motor symptoms of the disorder that would later bear his name, there is still an irrefutable need for a therapy that targets the underlying pathophysiology ...
Central CB2 receptors in inflammation-driven neurodegeneration: dysregulation and therapeutic potential
(Medknow Publications, 2016-10-19)
In recent times there has been an intensification of interest in the pathological role of neuroinflammation in neurodegenerative disease. Neuroprotective strategies to slow, halt or reverse neurodegeneration have not proven ...
A role for viral infections in Parkinson's etiology?
(Portland Press, 2018-04-16)
Despite over 200 years since its first description by James Parkinson, the cause(s) of most cases of Parkinson’s disease (PD) are yet to be elucidated. The disparity between the current understanding of PD symptomology and ...
In memory of Tom Isaacs: The epitomical mover and shaker
[No abstract available]