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MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer
(Biomed Central, 2010)
Background
Advances in high-throughput technologies and bioinformatics have transformed gene expression profiling methodologies. The results of microarray experiments are often validated using reverse transcription ...
Inhibition by Anandamide of 6-Hydroxydopamine-Induced Cell Death in PC12 Cells
(2010)
6-hydroxydopamine (6-OHDA) is a selective neurotoxin that is widely used to investigate cell death and protective strategies in models of Parkinson's disease. Here, we investigated the effects of the endogenous cannabinoid, ...
Incidental findings on MRI scans of patients presenting with audiovestibular symptoms
(Biomed Central, 2010)
Background:The evaluation of patients presenting with audiovestibular symptoms usually includes MRI of the internal auditory meatus, the cerebellopontine angle and the brain. A significant percentage of these scans will ...
Adverse events of fluoroquinolones vs. other antimicrobials prescribed in primary care: A systematic review and meta-analysis of randomized controlled trials
(Elsevier, 2018-04-25)
Background
Fluoroquinolones (FQs) are second line antimicrobial agents. Once the decision to prescribe
an antimicrobial is made, its choice should be based on both the benefits and harms. This
systematic review quantifies ...
miR-379 Regulates Cyclin B1 Expression and Is Decreased in Breast Cancer
(2013)
MicroRNAs are small non-coding RNA molecules that control gene expression post-transcriptionally, and are known
to be altered in many diseases including breast cancer. The aim of this study was to determine the relevance ...
Pharmacological inhibition of monoacylglycerol lipase attenuates LPS-induced increases in cytokine expression in the rat frontal cortex and plasma: differential mechanisms of action
(2013)
Background and purpose: This study determined the effect of JZL184, a selective inhibitor of monoacylglycerol lipase (MAGL), the enzyme which preferentially catabolises the endocannabinoid 2-arachidonoyl glycerol (2-AG), ...
The very first requirement of treatment is that it should do no harm†, so why are antibiotics still overprescribed?
(Wiley, 2014-01-26)
[No abstract available]
Epidemiology of gestational diabetes mellitus according to IADPSG/WHO 2013 criteria among obese pregnant women in Europe
(Springer Verlag, 2016-08-29)
Accurate prevalence estimates for gestational diabetes mellitus (GDM) amongst pregnant women in Europe are lacking due to the use of a multitude of diagnostic criteria and screening strategies in both high-risk women and ...
A comparison of the teamwork attitudes and knowledge of Irish surgeons and U.S Naval aviators.
(Elsevier, 2012-10)
Poor teamwork skills are contributors to poor performance and mishaps in high risk work settings, including the operating theatre. A questionnaire was used to assess the attitudes towards, and knowledge of, Irish surgeons ...
Detection of ROS induced proteomic signatures by mass spectrometry
(Frontiers Media, 2017)
Reversible and irreversible post-translational modifications ( PTMs) induced by endogenously generated reactive oxygen species (ROS) in regulatory enzymes and proteins plays an essential role in cellular signaling. Almost ...