Search
Now showing items 21-30 of 215
Minocycline modulates neuropathic pain behaviour and cortical M1-M2 microglial gene expression in a rat model of depression
(Elsevier, 2014-11)
There is a paucity of data on the role of microglia and neuroinflammatory processes in the association between chronic pain and depression. The current study examined the effect of the microglial inhibitor minocycline on ...
Cognitive course in first-episode psychosis and clinical correlates: A 4year longitudinal study using the MATRICS Consensus Cognitive Battery.
(2015-09-26)
While cognitive impairments are prevalent in first-episode psychosis, the course of these deficits is not fully understood. Most deficits appear to remain stable, however there is uncertainty regarding the trajectory of ...
Signaling pathways in mouse embryo stem cell self-renewal
(In Tech, 2011)
At the pre-implantation blastocyst stage of development, the mammalian embryo is
composed of a unique collection of cells of which three major populations predominate. The
outermost layer the trophectoderm (TE) gives ...
Application of video-based methods for competitive swimming analysis: a systematic review
(2015)
This paper explores the application of video-based methods for the analysis of com- petitive swimming performance. A systematic search of the existing literature was conducted using the following keywords: swim*, performance, ...
Neuroinflammatory mechanisms linking pain and depression
(Karger, 2015)
Depression and chronic pain have been estimated to co-occur in up to 80% of patients suffering from these disorders, with this co-morbidity being more disabling and more expensive to both patients and society than either ...
Using mobile phones to collect patient data: lessons learned from the SIMPle study
(JMIR Publications, 2017-04-25)
Background: Mobile phones offer new opportunities to efficiently and interactively collect real-time data from patients with acute illnesses, such as urinary tract infections (UTIs). One of the main benefits of using mobile ...
Impact of working 48 hours per week on opportunities for training and patient contact: the experience of Irish interns
(Oxford University Press, 2015-09-29)
Objective. The European Working Time Regulations (EWTR) have been criticised for its
purported negative impact on the training of junior doctors. The aim of this study was to examine
the amount of time interns spent ...
Anandamide modulation of endotoxin-induced inflammation
(OMICS International, 2013-12-20)
The endocannabinoid system is comprised of the CB1
and CB2
receptors, the naturally occurring endogenous ligands, anandamide
(AEA) and 2-arachidonyl glycerol (2-AG); and the enzymes
involved in their synthesis and ...
Minimum information about T Regulatory Cells: A step toward reproducibility and standardization
(Frontiers Media, 2018-01-15)
Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing ...
Anti-donor immune responses elicited by allogeneic mesenchymal stem cells and their extracellular vesicles: Are we still learning?
(Frontiers Media, 2017-11-24)
Mesenchymal stromal cells (MSC) have been used to treat a broad range of disease indications such as acute and chronic inflammatory disorders, autoimmune diseases, and transplant rejection due to their potent immunosuppr ...