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Minimum information about T Regulatory Cells: A step toward reproducibility and standardization
(Frontiers Media, 2018-01-15)
Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing ...
Adverse events of fluoroquinolones vs. other antimicrobials prescribed in primary care: A systematic review and meta-analysis of randomized controlled trials
(Elsevier, 2018-04-25)
Background
Fluoroquinolones (FQs) are second line antimicrobial agents. Once the decision to prescribe
an antimicrobial is made, its choice should be based on both the benefits and harms. This
systematic review quantifies ...
Shiga toxigenic Escherichia coli incidence is related to small area variation in cattle density in a region in Ireland
(Elsevier, 2018-05-12)
Shiga toxigenic Escherichia coli (STEC) are pathogenic E. coli that cause infectious diarrhoea. In some cases infection may be complicated by renal failure and death. The incidence of human infection with STEC in Ireland ...
Extracellular vesicles as modulators of wound healing
(Elsevier, 2018-01-31)
Impaired healing of cutaneous wounds and ulcers continues to have a major impact on the quality of life of millions of people. In recent years, the capacity for stem and progenitor cells to promote wound repair has been ...
Third-party allogeneic mesenchymal stromal cells prevent rejection in a pre-sensitized high-risk model of corneal transplantation
(Frontiers Media, 2018-11-20)
High-risk cornea transplant recipients represent a patient population with significant un-met medical need for more effective therapies to prevent immunological graft rejection due to heightened anti-donor immune response. ...
EIT image-based bladder state classification for nocturnal enuresis
(School of Engineering, The University of Edinburgh, 2018-06-11)
In this paper, we propose the use of electrical impedance tomography (EIT) to support children with nocturnal enuresis. We perform the first image-based threshold classification for determining the bladder state of not ...
The development of entrustable professional activities for the Irish intern year
(NUI Galway, 2018-09)
There have been significant reforms in intern training in Ireland over the last decade
to bring about improvements for the benefit of trainees, health services and ultimately the public. Activities undertaken by the Medical ...
Cell viability in three ex vivo rat models of spinal cord injury
(Wiley, 2018-11-11)
Spinal cord injury (SCI) is a devastating disorder that has a poor prognosis of recovery. Animal models of SCI are useful to understand the pathophysiology of SCI and the potential use of therapeutic strategies for human ...
In memory of Tom Isaacs: The epitomical mover and shaker
(Wiley, 2018-10-16)
[No abstract available]
Improving antimicrobial prescribing: a multinomial model identifying factors associated with first- and second-line prescribing
(Elsevier, 2018-12-13)
Background/objectives: Broad-spectrum, second-line antimicrobials may be prescribed when initial first-line options prove ineffective. This study compares prescribing practices and identifies potential influencing factors ...