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Regulating immunogenicity and tolerogenicity of bone marrow-derived dendritic cells through modulation of cell surface glycosylation by dexamethasone treatment
(Frontiers Media, 2017-10-30)
Dendritic cellular therapies and dendritic cell vaccines show promise for the treatment of autoimmune diseases, the prolongation of graft survival in transplantation, and in educating the immune system to fight cancers. ...
Free water elimination and mapping from diffusion tensor imaging (DTI) in chronic schizophrenia
(NUI Galway, 2017-06-11)
Diffusion tensor imaging (DTI) acquisitions allows the comparison of diffusion characteristics in vivo and gives a unique insight into tissue structure and pathology. However, a limitation of DTI post-processing is the ...
Structural connectivity and rich-club organization in recent onset psychosis
(Elsevier, 2017-05-17)
[No abstract available]
Is diabetes self-management education still the Cinderella of diabetes care?
(Elsevier ScienceDirect, 2017-05-17)
This paper reflects on the status of diabetes self-management education (DSME) as a branch of diabetology in Europe and discusses some opportunities for better supporting DSME delivery. DSME (also commonly known as Therapeutic ...
Investigating the management of diabetes in nursing homes using a mixed methods approach
(Elsevier ScienceDirect, 2017-03-21)
Aims: As populations age there is an increased demand for nursing home (NH) care and a parallel increase in the prevalence of diabetes. Despite this, there is growing evidence that the management of diabetes in NHs is ...
Using mobile phones to collect patient data: lessons learned from the SIMPle study
(JMIR Publications, 2017-04-25)
Background: Mobile phones offer new opportunities to efficiently and interactively collect real-time data from patients with acute illnesses, such as urinary tract infections (UTIs). One of the main benefits of using mobile ...
Anti-donor immune responses elicited by allogeneic mesenchymal stem cells and their extracellular vesicles: Are we still learning?
(Frontiers Media, 2017-11-24)
Mesenchymal stromal cells (MSC) have been used to treat a broad range of disease indications such as acute and chronic inflammatory disorders, autoimmune diseases, and transplant rejection due to their potent immunosuppr ...
Detection of ROS induced proteomic signatures by mass spectrometry
(Frontiers Media, 2017)
Reversible and irreversible post-translational modifications ( PTMs) induced by endogenously generated reactive oxygen species (ROS) in regulatory enzymes and proteins plays an essential role in cellular signaling. Almost ...
Adverse effects of amoxicillin for acute lower respiratory tract infection in primary care: Secondary and subgroup analysis of a randomised clinical trial
(MDPI, 2017-12-13)
A European placebo-controlled trial of antibiotic treatment for lower respiratory tract infection (LRTI) conducted in 16 primary care practices networks recruited participants between November 2007 and April 2010, and found ...
Strength in Numbers: an international consensus conference to develop a novel approach to care delivery for young adults with type 1 diabetes, the D1 Now Study
(BioMed Central, 2017-12-04)
Many young adults with type 1 diabetes struggle with the day-to-day management of their condition. They often find it difficult to find the time to attend their clinic appointments and to meet with their diabetes healthcare ...