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Preclinical evaluation of Millipede 088 intracranial aspiration catheter in cadaver and in vitro thrombectomy models
(BMJ Publishing Group, 2020-06-30)
Background Larger bore aspiration catheters are expected to significantly improve the speed and completeness of acute stroke revascularization.
Objective To evaluate the navigability and clot retrieval performance of a ...
Attenuation of fear‐conditioned analgesia in rats by monoacylglycerol lipase inhibition in the anterior cingulate cortex: Potential role for CB2 receptors
(The British Pharmacological Society, 2020-01-22)
Improved understanding of brain mechanisms regulating endogenous analgesia is important from a fundamental physiological perspective and for identification of novel therapeutic strategies for pain. The endocannabinoid ...
Dielectric profile of blood clots to inform ischemic stroke treatments
(IEEE, 2020-07-20)
Platelet and fibrin-rich blood clots can respond
differently to red blood cell rich clots during ischemic stroke
treatment, which includes thrombolysis and mechanical
thrombectomy. Currently, there is no accurate way ...
Antinociceptive effects of the GPR55 Antagonist CID16020046 injected into the rat anterior cingulate cortex
(Elsevier, 2020-07-13)
The G-protein coupled receptor, GPR55, modulates nociceptive processing. Given the expression of GPR55 in the anterior cingulate cortex (ACC), a key brain region involved in the cognitive and affective dimensions of pain, ...
Differential role of anterior cingulate cortical glutamatergic neurons in pain-related aversion learning and nociceptive behaviors in male and female rats
(Frontiers Media, 2020-08-11)
Pain is comprised of both sensory and affective components. The anterior cingulate cortex (ACC) is a key brain region involved in the emotional processing of pain. Specifically, glutamatergic transmission within the ACC ...
Pharmacological blockade of PPAR isoforms increases conditioned fear responding in the presence of nociceptive tone
(MDPI, 2020-02-24)
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors with three isoforms (PPAR¿, PPARß/¿, PPAR¿) and can regulate pain, anxiety, and cognition. However, their role in conditioned fear and pain-fear ...
ASPiH Conference 2019 keynote paper. Quality improvement through simulation: a missed opportunity?
(BMJ Publishing Group, 2020-03-04)
As the use of simulation has become more established in the delivery of healthcare education and training, there has been a corresponding increase in healthcare simulation research. Simulation-based research can be divided ...
A toolkit for improving hand hygiene compliance in intensive care
(National University of Ireland Galway, 2020-10-15)
A toolkit to help intensive care units to identify how they can improve hand hygiene compliance.
An introduction to human factors for healthcare workers
(Health Services Executive, 2021-11-20)
This document: (1) provides a comprehensive overview of human factors; (2) supports healthcare workers to identify the human factors issues in their workplace; (3) supports the identification of the human factors contributors ...
National strategic guide for the implementation of simulation on clinical sites
(National University of Ireland Galway, 2021-06)
[No abstract available]