Now showing items 1-5 of 5

    • Does bridging therapy in mechanical thrombectomy increase recanalization rates in ischemic stroke patients affected by acute large vessel occlusion? 

      Silva Santos, Andreia M.; Rossi, Rosanna; Pandit, Abhay; Fitzgerald, Seán; Mereuta, Oana Madalina; Douglas, Andrew; Thornton, John; Brennan, Paul; Power, Sarah; O’Hare, Alan; Rentzos, Alexandros; Ceder, Erik; Tatlisumak, Turgut; Jood, Katarina; Redfors, Petra; Nordanstig, Annika; Duffy, Sharon; Gilvarry, Michael; McCarthy, Ray; Doyle, Karen M. (SAGE Publications, 2019-05-22)
      Both intravenous thrombolysis with tissue plasminogen activator (IV-rtPA) and mechanical thrombectomy (MT) increase recanalization rates. We assessed if bridging-therapy (the concomitant use of rtPA and MT) could increase ...
    • Fatty acid binding protein expression in clots retrieved by mechanical thrombectomy from patients with acute ischaemic stroke 

      Mereuta, Oana Madalina; Fitzgerald, Seán; Douglas, Andrew; Rossi, Rosanna; Silva Santos, Andreia M.; Pandit, Abhay; Thornton, John; O'Hare, Alan; Power, Sarah; Brennan, Paul; Rentzos, Alexandros; Tatlisumak, Turgut; Gunnarsson, Thorsteinn; Davidson, Maria; Brederlau, Anke; Allardt, Arne; Brinjikji, Waleed; Kallmes, David F.; Doyle, Karen M. (Sage Publications, 2019-05-22)
      Introduction: Lipid accumulation and inflammation are considered hallmarks of the unstable atherosclerotic plaque. In particular, adipocyte fatty acid binding protein (FABP4) expression within the plaque is associated ...
    • Histological characterization of white clots retrieved by mechanical thrombectomy from acute ischemic stroke patients 

      Mereuta, Oana Madalina; Fitzgerald, Seán; Douglas, Andy; Rossi, Rosanna; Silva Santos, Andreia M.; Pandit, Abhay; Thornton, John; Rentzos, Alexandros; Tatlisumak, Turgut; Doyle, Karen M. (SAGE Publications, 2019-01-01)
      Introduction: Advances in mechanical thrombectomy have created the unique opportunity to study the acute ischemic stroke clot material. However, there is a lack of uniformity in the histopathologic characterization of ...
    • The impact of occlusion location and bridging therapy in patients affected by acute ischemic stroke in determining the total number of passes required to remove the clot and the final revascularization outcome 

      Rossi, Rosanna; Fitzgerald, Seán; Mereuta, Oana Madalina; Douglas, Andrew; Pandit, Abhay; Szikora, István; Tsivgoulis, Georgios; Psychogios, Klearchos; Murphy, Blathnaid; Brennan, Paul; Power, Sarah; O'Hare, Alan; Thornton, John; Rentzos, Alexandros; Tatlisumak, Turgut; Doyle, Karen M. (WFITN (World Federation of Interventional and Therapeutic Neuroradiology), 2019-10-21)
      Purpose Our purpose was to assess the impact of occlusion location in patients suffering from Acute Ischemic Stroke (AIS) on the total number of passes (attempts) necessary to retrieve the clot and on final revascularization ...
    • Platelet-rich emboli are associated with von Willebrand factor levels and have poorer revascularization outcomes 

      Douglas, Andrew; Fitzgerald, Seán; Mereuta, Oana Madalina; Rossi, Rosanna; O'Leary, Sean; Pandit, Abhay; McCarthy, Ray; Gilvarry, Michael; Holmegaard, Lukas; Abrahamsson, Margareta; Jerndal, Mikael; Dehlfors, Niclas; Brennan, Paul; Power, Sarah; O'Hare, Alan; Griffin, Emma; Kallmes, David F.; Brinjikji, Waleed; Szikora, István; Tatlisumak, Turgut; Rentzos, Alexandros; Thornton, John; Doyle, Karen M. (BMJ Publishing Group, 2019-11-04)
      Background and aims Platelets and von Willebrand factor (vWF) are key factors in thrombosis and thus are likely key components of acute ischemic stroke (AIS) emboli. We aimed to characterize platelet and vWF levels in AIS ...