Browsing School of Medicine by Author "Hardiman Research Scholarship, National University of Ireland Galway"
Now showing items 1-5 of 5
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FAAH inhibition attenuates TLR3-mediated hyperthermia, nociceptive- and anxiety-like behaviour in female rats
Flannery, Lisa E.; Kerr, Daniel M.; Finn, David P.; Roche, Michelle (Elsevier, 2018-06-25)Aberrant activation of toll-like receptor (TLR)s results in persistent and prolonged neuroinflammation and has been implicated in the pathogenesis and exacerbation of psychiatric and neurodegenerative disorders. TLR3 ... -
FAAH, but not MAGL, inhibition modulates acute TLR3‐induced neuroimmune signaling in the rat, independent of sex
Flannery, Lisa E.; Henry, Rebecca J.; Kerr, Daniel M.; Finn, David P.; Roche, Michelle (Wiley, 2017-07-20)Toll-like receptor (TLR)3 is a key component of the innate immune response to viral infection. The present study firstly examined whether sex differences exist in TLR3-induced inflammatory, endocrine, and sickness responses. ... -
Maternal presence or absence alters nociceptive responding and cortical anandamide levels in juvenile female rats
O’Sullivan, Grace; Humphrey, Rachel M.; Thornton, Aoife M.; Kerr, Daniel M.; McGuire, Brian E.; Caes, Line; Roche, Michelle (Elsevier, 2020-05-30)The influence of parental support on child pain experiences is well recognised. Accordingly, animal studies have revealed both short- and long-term effects of early life stress on nociceptive responding and neural substrates ... -
A systematic review of patient complaints about general practice
O’Dowd, Emily; Lydon, Sinéad; Madden, Caoimhe; O'Connor, Paul (Oxford University Press (OUP), 2019-11-19)Objective This review aimed to synthesize the extant research on complaints in general practice. Methods Five electronic databases were searched: Medline, Web of Science, CINAHL, PsycINFO and Academic Search Complete. ... -
A systematic review of patient complaints about general practice.
O'Dowd, Emily; Lydon, Sinéad; Madden, Caoimhe; O'Connor, Paul (Oxford University Press (OUP), 2019-11-19)Health care complaints are an underutilized resource for quality and safety improvement. Most research on health care complaints is focused on secondary care. However, there is also a need to consider patient safety in ...