Browsing School of Medicine by Title
Now showing items 72-91 of 336
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Curriculum development for sustainable civic engagement
(Educational Developers of Ireland Network, 2013)Capacity building both for students and for community partners is an explicit goal for one particular teaching and learning innovation in Irish higher education. In addition to offering the opportunity to apply ... -
Design of a smartphone application with integrated Functional Electrical Stimulation (FES) treatment randomization and On-The-Fly Stimulus Parameter Adjustment for streamlining the clinical evaluation of FES protocols
(OMICS International, 2016-03-14)The clinical application of Functional Electrical Stimulation (FES) has evolved over the last five decades. However, the use of the Randomized Control Trial (RCT) methodology in evaluating the clinical effectiveness of new ... -
Detection of ROS induced proteomic signatures by mass spectrometry
(Frontiers Media, 2017)Reversible and irreversible post-translational modifications ( PTMs) induced by endogenously generated reactive oxygen species (ROS) in regulatory enzymes and proteins plays an essential role in cellular signaling. Almost ... -
Detection, diagnosis and treatment of acute ischemic stroke: Current and future perspectives
(Frontiers Media, 2022-06-24)Stroke is one of the leading causes of disability worldwide. Early diagnosis and treatment of stroke are important for better clinical outcome. Rapid and accurate diagnosis of stroke subtypes is critical. This review ... -
Development and characterization of a novel, anatomically relevant rat model of acute postoperative pain
(Elsevier, 2015-01-30)Acute postoperative pain remains a significant health care issue. Development of anatomically relevant animal models of postoperative pain, with improved predictive validity, would advance understanding of postoperative ... -
The development of entrustable professional activities for the Irish intern year
(NUI Galway, 2018-09)There have been significant reforms in intern training in Ireland over the last decade to bring about improvements for the benefit of trainees, health services and ultimately the public. Activities undertaken by the Medical ... -
The development of translational biomarkers as a tool for improving the understanding, diagnosis and treatment of chronic neuropathic pain
(Springer, 2017-03-30)Chronic neuropathic pain (CNP) is one of the most significant unmet clinical needs in modern medicine. Alongside the lack of effective treatments, there is a great deficit in the availability of objective diagnostic methods ... -
Diabetes mellitus and gender have a negative impact on the outcome of hip fracture surgery – a pilot study
(Wiley, 2019-11-07)Diabetes mellitus (DM) is associated with an elevated risk of post-operative complications. The impact it has on patients living with DM following hip fracture surgery (HFS) is not completely understood, and may represent ... -
Diagnostic and therapeutic mesenchymal stem cells for breast cancer treatment
(Wiley, 2013-08-09)[No abstract available] -
Dielectric profile of blood clots to inform ischemic stroke treatments
(IEEE, 2020-07-20)Platelet and fibrin-rich blood clots can respond differently to red blood cell rich clots during ischemic stroke treatment, which includes thrombolysis and mechanical thrombectomy. Currently, there is no accurate way ... -
Dietary sodium and cardiovascular disease risk
(Massachusetts Medical Society, 2016-12-15)[No abstract available] -
Differential glycosylation expression in injured rat spinal cord treated with immunosuppressive drug Cyclosporin-A.
(American Chemical Society, 2019-02-12)Glycosylation is ubiquitous throughout the central nervous system and altered following spinal cord injury (SCI). The glial scar that forms following SCI is composed of several chondroitin sulfate proteoglycans, which ... -
Differential role of anterior cingulate cortical glutamatergic neurons in pain-related aversion learning and nociceptive behaviors in male and female rats
(Frontiers Media, 2020-08-11)Pain is comprised of both sensory and affective components. The anterior cingulate cortex (ACC) is a key brain region involved in the emotional processing of pain. Specifically, glutamatergic transmission within the ACC ... -
Distinctive effects of eicosapentaenoic and docosahexaenoic acids in regulating neural stem cell fate are mediated via endocannabinoid signalling pathways
(Elsevier, 2016-04-01)Emerging evidence suggests a complex interplay between the endocannabinoid system, omega-3 fatty acids and the immune system in the promotion of brain self-repair. However, it is unknown if all omega 3 fatty acids elicit ... -
Distribution of tract deficits in schizophrenia
(BioMed Central, 2014-04-02)Background: Gray and white matter brain changes have been found in schizophrenia but the anatomical organizing process underlying these changes remains unknown. We aimed to identify gray and white matter volumetric changes ... -
Disturbing effect of intra-tissue temperature sensors in pre-clinical experimental studies of radiofrequency cardiac ablation: A computer-based modeling study
(MDPI, 2023-04-11)Background: Preclinical studies on radiofrequency (RF) cardiac ablation (RFCA) use very small temperature sensors in specific positions in the tissue subjected to RF heating. Despite the sensors¿ small size, the proximity ... -
Do general practitioners prescribe more antimicrobials when the weekend comes?
(SpringerOpen, 2015-11-24)Inappropriate antimicrobial prescribing contributes to the global spread of antimicrobial resistance. The pending weekend with changed availability of general practitioners (GP) and increased patient concern may increase ... -
Does bridging therapy in mechanical thrombectomy increase recanalization rates in ischemic stroke patients affected by acute large vessel occlusion?
(SAGE Publications, 2019-05-22)Both intravenous thrombolysis with tissue plasminogen activator (IV-rtPA) and mechanical thrombectomy (MT) increase recanalization rates. We assessed if bridging-therapy (the concomitant use of rtPA and MT) could increase ... -
Does prior administration of rtPA influence acute ischemic stroke clot composition? Findings from the analysis of clots retrieved with mechanical thrombectomy from the RESTORE registry
(Springer, 2021-08-20)Background and purpose There is still much debate whether bridging-therapy [intravenous thrombolysis (IVT) prior to mechanical thrombectomy (MT)] might be beneficial compared to MT alone. We investigated the effect of IVT ...